Dysbiosis Enhancing Linkage Towards Association with Canine Osteosarcoma (DEL-TACO Lite)
Currently EnrollingEthos Discovery de novo study
Description
Intestinal dysbiosis is an alteration in the composition and/or richness of the normal bacterial population in the intestines. It has been suggested that states of intestinal dysbiosis exist and may possibly correlate with various diseases, such as cancer and immune-mediated diseases. The effect of intestinal dysbiosis on the progression of various diseases is currently lacking in both human and veterinary medicine.
Ethos Discovery now asks what the influence of intestinal dysbiosis is on a variety of non-GI diseases in veterinary patients. Intestinal dysbiosis has been associated with tumor progression of colorectal, lung, and breast cancer in human patients. To date, no studies have been published investigating the intestinal microbiome in dogs or humans with osteosarcoma (OSA). The objective of this study is to determine whether or not canine patients diagnosed with OSA have intestinal dysbiosis and if the presence of intestinal dysbiosis is associated with metastasis in these patients.
Eligibility criteria
- Dogs with osteosarcoma confirmed on biopsy (with or without evidence of metastasis).
Participating hospitals
Any patient from any hospital in the world can participate in this study, as long as the patient has a biopsy result confirming the diagnosis. If you have a patient who may be eligible to participate in the study, please submit the form below, we will be in touch to discuss the patient and next steps for submitting the samples.
Interested?
Inquire about your dog’s eligibility or request more information below